Congenital absence/hypoplasia of fingers excluding thumb, unilateral is a condition in which one hand has fewer than five fingers, excluding the thumb. This condition is usually present at birth and is caused by a genetic mutation or environmental factors. It can cause physical and functional impairments, such as difficulty with fine motor skills and gripping objects. Treatment may include physical therapy, occupational therapy, and surgery.

Symptoms of congenital absence/hypoplasia of fingers excluding thumb, unilateral may include:

-A hand with fewer than five fingers
-A hand with a smaller than normal size
-A hand with an abnormal shape
-A hand with a webbed or fused appearance
-A hand with a missing or underdeveloped thumb
-A hand with a missing or underdeveloped index finger
-A hand with a missing or underdeveloped middle finger
-A hand with a missing or underdeveloped ring finger
-A hand with a missing or underdeveloped pinky finger
-A hand with a missing or underdeveloped nail
-A hand with a missing or underdeveloped knuckle
-A hand with a missing or underdeveloped palm
-A hand with a missing or underdeveloped wrist joint
-A hand with a missing or underdeveloped

1. Genetic mutations: Certain genetic mutations can cause congenital absence/hypoplasia of fingers, excluding the thumb, on one side of the body.

2. Chromosomal abnormalities: Chromosomal abnormalities, such as trisomy 13, can cause congenital absence/hypoplasia of fingers, excluding the thumb, on one side of the body.

3. Maternal infections: Maternal infections, such as rubella, during pregnancy can cause congenital absence/hypoplasia of fingers, excluding the thumb, on one side of the body.

4. Trauma: Trauma to the fetus during pregnancy can cause congenital absence/hypoplasia of fingers, excluding the thumb, on one side of the body.

5. Exposure to certain medications: Exposure to certain medications, such as thalidomide

1. Splinting: Splinting is a common treatment for congenital absence/hypoplasia of fingers excluding thumb, unilateral. Splints can be used to help maintain the position of the affected fingers and to help prevent contractures.

2. Surgery: Surgery may be recommended to correct the deformity and improve the function of the affected fingers. Surgery may involve tendon transfers, joint fusion, or bone grafts.

3. Physical Therapy: Physical therapy can help improve range of motion and strength in the affected fingers.

4. Occupational Therapy: Occupational therapy can help improve the function of the affected fingers and help the patient adapt to daily activities.

5. Prosthetics: Prosthetics can be used to replace missing fingers and improve the function of the affected hand.

1. Genetic factors: Certain genetic syndromes, such as Holt-Oram syndrome, can increase the risk of congenital absence/hypoplasia of fingers excluding thumb, unilateral.

2. Maternal factors: Maternal exposure to certain medications, such as anticonvulsants, during pregnancy can increase the risk of this condition.

3. Environmental factors: Exposure to certain environmental toxins, such as lead, during pregnancy can increase the risk of this condition.

4. Family history: Having a family history of congenital absence/hypoplasia of fingers excluding thumb, unilateral can increase the risk of this condition.

There is no cure for congenital absence/hypoplasia of fingers excluding thumb, unilateral. However, there are treatments available to help improve the function of the affected hand. These treatments may include physical therapy, occupational therapy, splinting, and surgery. Medications may also be prescribed to help manage pain and swelling.