Split Hand/Split Foot Malformation (SHFM) is a rare congenital disorder that affects the development of the hands and feet. It is characterized by the presence of extra digits, webbing between the fingers and toes, and/or fusion of the digits. It is caused by a mutation in the gene that controls the development of the hands and feet. Treatment typically involves surgery to correct the deformities and improve function.

The most common symptoms of Split Hand/Split Foot Malformation (SHFM) include:
* Abnormal webbing or fusion of the fingers and/or toes
* Abnormal shortening of the fingers and/or toes
* Abnormal positioning of the fingers and/or toes
* Abnormal shape of the fingers and/or toes
* Abnormal nail development
* Abnormal skin creases on the palms and/or soles of the feet
* Abnormal joint development
* Abnormal muscle development
* Abnormal bone development
* Abnormal tendon development
* Abnormal ligament development
* Abnormal nerve development
* Abnormal blood vessel development
* Abnormal skin pigmentation
* Abnormal sensation in the affected area

Split Hand/Split Foot Malformation (SHFM) is a rare congenital disorder caused by a genetic mutation. The exact cause of the mutation is unknown, but it is believed to be caused by a combination of genetic and environmental factors. Possible causes include exposure to certain medications, radiation, or chemicals during pregnancy, as well as a family history of the disorder.

1. Surgery: Surgery is the most common treatment for Split Hand/Split Foot Malformation. Surgery can be used to correct the deformity and improve the function of the affected hand or foot.

2. Physical Therapy: Physical therapy can help improve the strength and range of motion of the affected hand or foot.

3. Orthotics: Orthotics can be used to provide support and stability to the affected hand or foot.

4. Splints: Splints can be used to help keep the affected hand or foot in the correct position.

5. Occupational Therapy: Occupational therapy can help improve the function of the affected hand or foot.

6. Medications: Medications can be used to reduce pain and inflammation associated with Split Hand/Split Foot Malformation.

1. Genetic mutations: Split Hand/Split Foot Malformation is caused by genetic mutations in the HOXD13 gene.

2. Family history: A family history of Split Hand/Split Foot Malformation increases the risk of developing the condition.

3. Maternal diabetes: Maternal diabetes during pregnancy increases the risk of Split Hand/Split Foot Malformation in the fetus.

4. Maternal alcohol use: Maternal alcohol use during pregnancy increases the risk of Split Hand/Split Foot Malformation in the fetus.

5. Maternal smoking: Maternal smoking during pregnancy increases the risk of Split Hand/Split Foot Malformation in the fetus.

Split Hand/Split Foot Malformation is a congenital disorder, meaning it is present at birth. There is no cure for this condition, but there are treatments available to help manage the symptoms. These treatments may include physical therapy, orthopedic surgery, and the use of orthotic devices. Medications may also be prescribed to help manage pain and discomfort.