Primary peritoneal serous/papillary carcinoma is a rare type of cancer that affects the lining of the abdomen (peritoneum). It is a type of epithelial ovarian cancer, meaning it begins in the cells that line the ovaries. It is usually found in women over the age of 50 and is often mistaken for ovarian cancer. Symptoms may include abdominal pain, bloating, and feeling full quickly after eating. Treatment typically involves surgery and chemotherapy.

The most common symptoms of primary peritoneal serous/papillary carcinoma are abdominal pain, bloating, nausea, vomiting, and weight loss. Other symptoms may include fatigue, loss of appetite, and changes in bowel habits. In some cases, the cancer may cause fluid to accumulate in the abdomen, which can cause swelling and discomfort.

The exact cause of primary peritoneal serous/papillary carcinoma is unknown. However, some risk factors have been identified, including a history of ovarian cancer, a family history of ovarian cancer, and certain genetic mutations. Other potential risk factors include exposure to certain chemicals, such as asbestos, and certain lifestyle factors, such as obesity.

The primary treatment for primary peritoneal serous/papillary carcinoma is surgery. Depending on the stage of the cancer, this may involve removing the tumor and any affected organs, such as the uterus, ovaries, or fallopian tubes. In some cases, chemotherapy and radiation therapy may be used to shrink the tumor before surgery or to reduce the risk of recurrence. In advanced cases, chemotherapy may be used to control the cancer and improve symptoms.

1. Advanced age
2. Female gender
3. Family history of ovarian cancer
4. History of endometriosis
5. History of infertility
6. History of pelvic radiation
7. Obesity
8. Nulliparity (never having given birth)
9. Long-term use of hormone replacement therapy (HRT)
10. Genetic mutations in the BRCA1 or BRCA2 genes

At this time, there is no known cure for primary peritoneal serous/papillary carcinoma. Treatment options may include surgery, chemotherapy, radiation therapy, and targeted therapy. Your doctor will be able to discuss the best treatment options for you.