Isolated congenital hypoglossia/aglossia is a rare condition in which a person is born without a tongue or with a very small tongue. It is caused by a genetic mutation and can lead to difficulty speaking, eating, and swallowing. People with this condition may also have difficulty with facial expressions and may have a cleft palate. Treatment typically involves speech therapy, occupational therapy, and surgery to help improve the person's ability to communicate and eat.

The main symptom of isolated congenital hypoglossia/aglossia is the absence of the tongue. Other symptoms may include difficulty speaking, difficulty swallowing, and difficulty eating. In some cases, the tongue may be small or underdeveloped. Other associated symptoms may include a cleft palate, hearing loss, and/or facial asymmetry.

The exact cause of isolated congenital hypoglossia/aglossia is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Possible causes include genetic mutations, prenatal infections, and exposure to certain toxins.

1. Speech therapy: Speech therapy can help children with isolated congenital hypoglossia/aglossia to learn to communicate effectively. Speech therapists can help children learn to use their tongue, lips, and other facial muscles to produce speech sounds.

2. Surgery: Surgery may be recommended for some cases of isolated congenital hypoglossia/aglossia. Surgery can help to improve the shape and size of the tongue, allowing for better speech production.

3. Augmentative and alternative communication (AAC): AAC is a form of communication that uses symbols, pictures, or other methods to help people communicate. AAC can be used to help children with isolated congenital hypoglossia/aglossia to communicate their needs and wants.

4. Assistive technology: Assistive technology can help children with isolated congenital hyp

1. Genetic mutations
2. Chromosomal abnormalities
3. Maternal infections
4. Maternal drug use
5. Maternal exposure to environmental toxins
6. Maternal diabetes
7. Maternal smoking
8. Low birth weight
9. Premature birth
10. Family history of congenital hypoglossia/aglossia

At this time, there is no known cure for isolated congenital hypoglossia/aglossia. However, there are treatments available to help improve speech and language development. These treatments may include speech therapy, augmentative and alternative communication (AAC) devices, and surgical interventions. Medications may also be prescribed to help manage associated symptoms such as drooling.