White sponge nevus is a rare, inherited disorder of the mucous membranes of the mouth. It is characterized by white, thickened patches of tissue on the inside of the cheeks, lips, and tongue. The condition is usually painless, but can cause discomfort and difficulty eating. It is caused by a mutation in the KRT4 gene. Treatment is not usually necessary, but may include topical medications or surgery to remove the affected tissue.

The most common symptom of white sponge nevus is the presence of white, velvety patches on the inside of the mouth, usually on the cheeks, tongue, and/or palate. These patches may be slightly raised and may have a cobblestone-like texture. They may also be accompanied by a Burning or Itching sensation. In some cases, the patches may become red and inflamed. Other symptoms may include difficulty eating, speaking, or swallowing, as well as bad breath.

White sponge nevus is a rare genetic disorder that is caused by a mutation in the KRT4 gene. This gene is responsible for producing a protein that helps form the structure of the skin. The mutation causes the skin to produce too much of this protein, resulting in the formation of white, spongy patches on the mucous membranes of the mouth and other areas of the body.

The treatment for white sponge nevus is usually not necessary, as the condition is usually harmless and does not cause any symptoms. However, if the lesions are causing discomfort or embarrassment, treatment options may include:

1. Topical medications: These may include corticosteroids, retinoids, or antifungal creams.

2. Laser therapy: This can be used to reduce the size of the lesions and improve their appearance.

3. Surgery: This may be necessary if the lesions are large or causing discomfort.

4. Cryotherapy: This involves freezing the lesions with liquid nitrogen.

The exact cause of white sponge nevus is unknown, but there are several risk factors that may increase the likelihood of developing the condition. These include:

• Family history of white sponge nevus
• Exposure to certain chemicals or environmental toxins
• Certain genetic mutations
• Certain medications or medical treatments
• Certain skin conditions, such as psoriasis or eczema
• Certain medical conditions, such as diabetes or HIV/AIDS

White sponge nevus is a rare genetic disorder that affects the mucous membranes of the mouth. There is no known cure for this condition, but medications such as topical corticosteroids and antifungal agents may be used to reduce the symptoms. Additionally, surgical removal of the affected tissue may be recommended in some cases.