About Visceral calciphylaxis

What is Visceral calciphylaxis?

Visceral calciphylaxis is a rare and potentially fatal condition that occurs when calcium deposits form in the small blood vessels of the visceral organs, such as the liver, spleen, and kidneys. It is most commonly seen in people with end-stage renal disease, diabetes, and obesity. Symptoms include abdominal pain, nausea, vomiting, and jaundice. Treatment typically involves medications to reduce calcium levels, as well as surgery to remove the calcium deposits.

What are the symptoms of Visceral calciphylaxis?

The symptoms of Visceral calciphylaxis include:

-Painful, purplish-Red skin lesions, usually on the abdomen, thighs, and buttocks
-Skin ulcers that may be slow to heal
-Fever
-Fatigue
-Nausea
-Weight loss
-Anemia
-Joint pain
-Muscle weakness
-Abdominal pain
-Itching
-Swelling of the legs and feet

What are the causes of Visceral calciphylaxis?

The exact cause of visceral calciphylaxis is unknown, but it is thought to be related to an imbalance of calcium and phosphate in the body. Other possible causes include:

• Kidney failure

• Dialysis

• Diabetes

• Hyperparathyroidism

• Certain medications

• Obesity

• Smoking

• Alcoholism

• Certain infections

• Certain genetic conditions

What are the treatments for Visceral calciphylaxis?

1. Treating the underlying cause of the condition: This may include treating any underlying medical conditions, such as kidney disease, diabetes, or liver disease.

2. Medications: Medications such as cinacalcet, warfarin, and sevelamer may be prescribed to help reduce calcium levels in the blood.

3. Surgery: In some cases, surgery may be necessary to remove the affected tissue.

4. Dialysis: Dialysis may be necessary if the kidneys are not functioning properly.

5. Nutrition: A diet low in calcium and phosphorus may be recommended to help reduce the risk of further calcification.

6. Hyperbaric oxygen therapy: This therapy may be used to help reduce the risk of further calcification.

What are the risk factors for Visceral calciphylaxis?

1. End-stage renal disease
2. Dialysis
3. Diabetes
4. Hyperparathyroidism
5. Hyperlipidemia
6. Obesity
7. Hypertension
8. Chronic liver disease
9. Use of certain medications, such as calcium-containing phosphate binders, calcitriol, and vitamin D analogs
10. Recent surgery or trauma
11. Smoking
12. Advanced age

Is there a cure/medications for Visceral calciphylaxis?

At this time, there is no known cure for Visceral calciphylaxis. Treatment typically involves medications to reduce calcium levels in the blood, such as cinacalcet, and medications to reduce inflammation, such as corticosteroids. Other treatments may include dialysis, surgery, and medications to reduce the risk of blood clots.