Usher syndrome type 2 is a rare genetic disorder that affects both hearing and vision. It is characterized by progressive hearing loss and vision loss due to retinitis pigmentosa (RP). People with Usher syndrome type 2 typically experience hearing loss from birth or early childhood, and vision loss usually begins in the teenage years.

The symptoms of Usher syndrome type 2 include:

-Progressive hearing loss
-Balance problems
-Vision loss, usually beginning in the teenage years
-Difficulty seeing in low light
-Difficulty recognizing faces
-Difficulty with depth perception
-Trouble with hand-eye coordination
-Difficulty with mobility and navigating unfamiliar environments
-Difficulty with reading and writing
-Difficulty with speech and language development

Usher Syndrome type 2 is caused by mutations in the USH2A gene. This gene provides instructions for making a protein called usherin, which is involved in the development and maintenance of the inner ear and retina. Mutations in the USH2A gene can lead to the hearing and vision problems associated with Usher Syndrome type 2.

The treatments for Usher syndrome type 2 vary depending on the individual and the severity of their symptoms. Generally, treatments focus on managing the symptoms of hearing loss, vision loss, and balance problems. These may include hearing aids, cochlear implants, glasses, low vision aids, physical therapy, and balance exercises. Additionally, genetic counseling may be recommended to help individuals and their families understand the condition and plan for the future.

The primary risk factor for Usher syndrome type 2 is having a parent who carries the gene mutation associated with the condition. Other risk factors include being of Ashkenazi Jewish descent, having a family history of Usher syndrome, and having a parent with a hearing or vision impairment.

There is no cure for Usher syndrome type 2, but there are medications and treatments that can help manage the symptoms. These include hearing aids, cochlear implants, and vision aids such as magnifiers and low vision aids. Additionally, physical and occupational therapy can help with balance and coordination.