Unilateral congenital megacalycosis is a rare condition in which one of the kidneys is abnormally large. It is caused by an abnormal development of the kidney during fetal development. Symptoms may include abdominal pain, fever, and urinary tract infections. Treatment typically involves surgical removal of the affected kidney.

The most common symptoms of unilateral congenital megacalycosis include:

-Enlarged kidney on one side of the body
-Abdominal swelling
-High blood pressure
-Proteinuria (excess protein in the urine)
-Hematuria (blood in the urine)
-Frequent urination
-Pain in the abdomen or flank
-Nausea and vomiting
-Fever
-Fatigue
-Weight loss

The exact cause of unilateral congenital megacalycosis is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Possible causes include:

- Abnormal development of the lymphatic system
- Abnormal development of the lymph nodes
- Abnormal development of the lymphatic vessels
- Congenital malformations of the lymphatic system
- Infections
- Trauma
- Immune system disorders
- Certain medications
- Radiation therapy

1. Surgery: Surgery is the most common treatment for unilateral congenital megacalycosis. The goal of surgery is to remove the enlarged cyst and any associated tissue.

2. Antibiotics: Antibiotics may be prescribed to reduce the risk of infection.

3. Drainage: If the cyst is causing a blockage, a drainage procedure may be necessary to relieve the pressure.

4. Medication: Medications such as diuretics may be prescribed to reduce the size of the cyst.

5. Physical Therapy: Physical therapy may be recommended to help improve mobility and reduce pain.

1. Genetic predisposition
2. Maternal diabetes
3. Maternal obesity
4. Maternal smoking
5. Maternal alcohol consumption
6. Maternal use of certain medications
7. Maternal exposure to certain environmental toxins
8. Maternal age over 35
9. Family history of congenital megacalycosis

At this time, there is no known cure for unilateral congenital megacalycosis. Treatment typically involves medications to reduce the size of the affected kidney and to reduce the risk of infection. These medications may include antibiotics, diuretics, and anti-inflammatory drugs. Surgery may also be recommended to remove the affected kidney or to reduce the size of the affected kidney.