Transient hyperammonemia of the newborn (THAN) is a rare metabolic disorder that occurs in newborns. It is caused by an inability of the newborn's liver to process ammonia, a byproduct of protein metabolism. Symptoms of THAN include vomiting, lethargy, poor feeding, and seizures. Treatment typically involves dietary changes and medications to reduce ammonia levels.

The symptoms of Transient hyperammonemia of the newborn include:

-Poor feeding
-Vomiting
-Lethargy
-Irritability
-Seizures
-Coma
-Respiratory distress
-Hypotonia
-Hyperventilation
-Hypoglycemia
-Hyperammonemia
-Elevated liver enzymes
-Jaundice
-Ascites
-Hepatomegaly

1. Urea cycle enzyme deficiencies
2. Organic acidemias
3. Inborn errors of metabolism
4. Intrauterine exposure to certain drugs
5. Maternal diabetes
6. Intrauterine infection
7. Prematurity
8. Sepsis
9. Hypoxic-ischemic encephalopathy
10. Liver dysfunction

1. Restriction of dietary protein intake
2. Administration of intravenous glucose
3. Administration of intravenous sodium benzoate
4. Administration of intravenous arginine
5. Administration of intravenous citrulline
6. Administration of intravenous carnitine
7. Administration of intravenous sodium phenylbutyrate
8. Administration of intravenous glycerol
9. Administration of intravenous sodium phenylacetate
10. Administration of intravenous sodium phenylacetate and sodium benzoate

1. Prematurity
2. Low birth weight
3. Maternal diabetes
4. Maternal obesity
5. Maternal use of certain medications, such as valproic acid
6. Maternal infection
7. Maternal malnutrition
8. Intrauterine growth restriction
9. Postnatal sepsis
10. Inborn errors of metabolism
11. Congenital anomalies
12. Neonatal hypoglycemia
13. Neonatal hypocalcemia
14. Neonatal hypothermia
15. Neonatal hypoxia
16. Neonatal acidosis
17. Neonatal jaundice
18. Neonatal asphyxia
19. Neonatal sepsis
20. Neonatal respiratory distress syndrome
21. Neonatal shock
22. Neonatal polycythemia
23.

Yes, there is a cure for transient hyperammonemia of the newborn. Treatment typically involves providing the newborn with intravenous fluids and electrolytes, as well as medications to reduce the levels of ammonia in the blood. In some cases, the newborn may also need to be given a special formula that is low in protein. In severe cases, the newborn may need to be given a liver transplant.