Torsade-de-pointes syndrome with short coupling interval is a type of ventricular tachycardia (VT) characterized by a rapid, irregular heart rhythm. It is caused by a shortening of the time between two consecutive heartbeats, known as the coupling interval. This can lead to a decrease in the amount of blood pumped out of the heart, which can cause symptoms such as dizziness, lightheadedness, and fainting. In some cases, it can also lead to cardiac arrest. Treatment typically involves medications to slow the heart rate and restore normal rhythm.

The symptoms of Torsade-de-pointes syndrome with short coupling interval include:

-Palpitations
-Lightheadedness
-Dizziness
-Syncope (fainting)
-Shortness of breath
-Chest pain
-Abnormal heart rhythms (arrhythmias)
-Cardiac arrest

1. Long QT Syndrome: This is a genetic disorder that affects the electrical activity of the heart and can cause Torsade-de-pointes syndrome with short coupling interval.

2. Certain medications: Certain medications, such as certain antibiotics, antiarrhythmic drugs, and antipsychotics, can cause Torsade-de-pointes syndrome with short coupling interval.

3. Electrolyte imbalances: Imbalances in electrolytes, such as potassium, magnesium, and calcium, can cause Torsade-de-pointes syndrome with short coupling interval.

4. Structural heart disease: Structural heart disease, such as cardiomyopathy, can cause Torsade-de-pointes syndrome with short coupling interval.

5. Abnormal heart rhythms: Abnormal heart rhythms,

1. Immediate electrical cardioversion
2. Intravenous magnesium sulfate
3. Intravenous isoproterenol
4. Intravenous procainamide
5. Intravenous lidocaine
6. Intravenous amiodarone
7. Intravenous sotalol
8. Intravenous flecainide
9. Intravenous ibutilide
10. Intravenous propafenone

1. Congenital long QT syndrome
2. Hypokalemia
3. Hypomagnesemia
4. Hypocalcemia
5. Medications that prolong the QT interval
6. Structural heart disease
7. Female gender
8. Advanced age
9. Congenital heart block
10. Bradycardia

At this time, there is no cure for Torsade-de-pointes syndrome with short coupling interval. However, medications such as beta-blockers, calcium channel blockers, and magnesium sulfate can be used to help manage the symptoms. Additionally, lifestyle modifications such as avoiding certain medications, reducing stress, and avoiding alcohol can help reduce the risk of developing the condition.