Thoracolumbosacral spina bifida aperta is a type of spina bifida, a birth defect in which the spine does not form properly. It is a rare form of spina bifida that affects the thoracic, lumbar, and sacral vertebrae. It is characterized by an opening in the spine, which can cause nerve damage and other complications. Treatment typically involves surgery to close the opening and protect the spinal cord.

The symptoms of thoracolumbosacral spina bifida aperta can vary depending on the severity of the condition. Common symptoms include:

- Abnormal curvature of the spine
- Weakness or Paralysis of the legs
- Loss of sensation in the legs
- Abnormal gait
- Urinary and/or bowel incontinence
- Abnormal development of the hips and legs
- Abnormal development of the spinal cord
- Abnormal development of the ribs
- Abnormal development of the vertebrae
- Abnormal development of the skin around the spine

Thoracolumbosacral spina bifida aperta is a rare form of spina bifida, a birth defect that occurs when the spine and spinal cord do not form properly. The exact cause of this condition is unknown, but it is believed to be related to a combination of genetic and environmental factors. Possible risk factors include a family history of spina bifida, certain medications taken during pregnancy, and maternal health conditions such as diabetes or obesity.

The treatment for thoracolumbosacral spina bifida aperta depends on the severity of the condition. Generally, treatment includes surgery to close the spinal defect, physical therapy to help with mobility, and medications to manage pain and other symptoms. In some cases, a shunt may be placed to help drain excess fluid from the brain or spine. Other treatments may include orthopedic braces, wheelchairs, and other assistive devices.

1. Family history of neural tube defects
2. Maternal diabetes
3. Maternal obesity
4. Maternal use of certain medications, such as anticonvulsants, during pregnancy
5. Maternal exposure to certain environmental toxins, such as pesticides
6. Maternal folic acid deficiency
7. Maternal age over 35
8. Low socioeconomic status

There is no cure for thoracolumbosacral spina bifida aperta, but there are medications and treatments that can help manage the symptoms. These include physical therapy, medications to reduce pain and spasticity, and surgery to correct any deformities or to close the spinal opening.