Synpolydactyly type 2 is a rare genetic disorder characterized by the presence of extra fingers or toes. It is caused by a mutation in the HOXD13 gene, which is responsible for the development of the limbs. People with this condition may have extra fingers or toes on one or both hands and feet, and the extra digits may be fused together. In some cases, the extra digits may be webbed or have extra bones. Treatment typically involves surgical removal of the extra digits.

The symptoms of Synpolydactyly type 2 include extra fingers or toes, webbing between the fingers or toes, and a wide gap between the big toe and the second toe. Other symptoms may include a short thumb, a curved fifth finger, and a wide gap between the fourth and fifth toes.

Synpolydactyly type 2 is caused by a genetic mutation in the HOXD13 gene. This gene is responsible for controlling the development of the limbs during embryonic development. Mutations in this gene can cause the extra digits to form.

The main treatment for Synpolydactyly type 2 is surgical removal of the extra digits. This is usually done in the first few months of life. Other treatments may include physical therapy to help with mobility and range of motion, splinting to help with positioning, and orthotics to help with alignment.

1. Family history of Synpolydactyly type 2
2. Maternal diabetes
3. Maternal obesity
4. Maternal smoking
5. Maternal alcohol consumption
6. Maternal use of certain medications
7. Advanced maternal age
8. Low birth weight
9. Premature birth

At this time, there is no known cure for Synpolydactyly type 2. However, there are several treatments available to help manage the condition. These include physical therapy, orthopedic surgery, and medications to reduce pain and inflammation.