Synpolydactyly type 1 is a rare genetic disorder characterized by the presence of extra fingers or toes. It is caused by a mutation in the HOXD13 gene, which is responsible for the development of the limbs. People with this condition may have extra fingers or toes on one or both hands and feet, and the extra digits may be fused together. In some cases, the extra digits may be webbed or have extra bones. Treatment typically involves surgical removal of the extra digits.

The most common symptoms of Synpolydactyly type 1 include extra fingers or toes, webbing between the fingers or toes, and abnormally shaped or fused digits. Other symptoms may include a shortening of the affected limb, a curved or bent finger or toe, and a wide gap between the thumb and index finger.

Synpolydactyly type 1 is caused by a genetic mutation in the HOXD13 gene. This gene is responsible for controlling the development of the limbs during embryonic development. Mutations in this gene can cause the extra digits to form.

The primary treatment for Synpolydactyly type 1 is surgical removal of the extra digits. This is usually done in the first few months of life. Other treatments may include physical therapy to help with mobility and range of motion, splinting to help with positioning, and orthotics to help with alignment.

1. Family history: Synpolydactyly type 1 is an inherited condition, so having a family history of the condition increases the risk of developing it.

2. Gender: Synpolydactyly type 1 is more common in males than females.

3. Ethnicity: Synpolydactyly type 1 is more common in people of African descent.

4. Maternal age: Women over the age of 35 are more likely to have a child with Synpolydactyly type 1.

At this time, there is no cure for Synpolydactyly type 1. However, there are treatments available to help manage the condition. These include surgery to remove extra digits, physical therapy to help improve range of motion, and orthotics to help support the affected limb. Medications may also be prescribed to help manage pain and inflammation.