Subependymal giant cell astrocytoma (SEGA) is a rare, slow-growing brain tumor that typically occurs in children and young adults with tuberous sclerosis complex (TSC). It is a type of astrocytoma, a tumor that arises from star-shaped cells in the brain called astrocytes. SEGA typically forms near the ventricles, the fluid-filled cavities in the brain, and can cause hydrocephalus, a buildup of fluid in the brain. Treatment typically involves surgical removal of the tumor, followed by medication to control symptoms and reduce the risk of recurrence.

The most common symptom of Subependymal giant cell astrocytoma (SEGA) is increased pressure in the brain, which can cause headaches, vomiting, and vision changes. Other symptoms may include seizures, developmental delays, and behavioral changes. In some cases, SEGA can cause hydrocephalus, which is an accumulation of fluid in the brain that can lead to further neurological problems.

Subependymal giant cell astrocytoma (SEGA) is a rare, benign brain tumor that is associated with the genetic disorder tuberous sclerosis complex (TSC). The exact cause of SEGA is unknown, but it is believed to be related to genetic mutations in the TSC1 or TSC2 genes. These mutations cause an overgrowth of cells in the brain, leading to the formation of SEGA.

The primary treatment for Subependymal giant cell astrocytoma (SEGA) is surgical resection. Depending on the size and location of the tumor, this may involve a craniotomy or endoscopic resection. In some cases, radiation therapy may be used to reduce the size of the tumor prior to surgery. In cases where the tumor is not amenable to surgical resection, medications such as mTOR inhibitors may be used to slow the growth of the tumor. In some cases, chemotherapy may be used to reduce the size of the tumor.

1. Tuberous sclerosis complex (TSC)
2. Neurofibromatosis type 1 (NF1)
3. Li-Fraumeni syndrome
4. Beckwith-Wiedemann syndrome
5. Familial adenomatous polyposis
6. Von Hippel-Lindau syndrome
7. Hereditary paraganglioma syndrome
8. Carney complex
9. Multiple endocrine neoplasia type 1
10. Cowden syndrome

Subependymal giant cell astrocytoma (SEGA) is a rare type of brain tumor that is usually found in people with tuberous sclerosis complex (TSC). Treatment for SEGA typically involves surgery to remove the tumor, followed by medications to control seizures and other symptoms. Medications used to treat SEGA include anticonvulsants, antipsychotics, and mTOR inhibitors. In some cases, radiation therapy may also be used.