Streptococcus pneumoniae-associated hemolytic uremic syndrome (SP-HUS) is a rare but serious complication of an infection with Streptococcus pneumoniae, a type of bacteria. It is characterized by hemolytic anemia (destruction of red blood cells), thrombocytopenia (low platelet count), and acute kidney failure. It is most commonly seen in children, but can also occur in adults. Treatment typically involves antibiotics and supportive care.

The symptoms of Streptococcus pneumoniae-associated hemolytic uremic syndrome (HUS) include:

- Abdominal pain
- Nausea and vomiting
- Diarrhea
- Fatigue
- Pale skin
- Dark urine
- Decreased urination
- Swelling of the face, hands, and feet
- Confusion
- Seizures
- Coma

Streptococcus pneumoniae-associated hemolytic uremic syndrome (HUS) is a rare but serious complication of a Streptococcus pneumoniae infection. It is caused by the release of toxins from the bacteria that damage the lining of the blood vessels, leading to the destruction of red blood cells and kidney failure. The exact cause of HUS is not known, but it is thought to be related to an immune response to the bacteria. Risk factors for developing HUS include being very young or very old, having a weakened immune system, and having certain underlying medical conditions.

The treatment for Streptococcus pneumoniae-associated hemolytic uremic syndrome (HUS) typically involves supportive care, such as intravenous fluids, blood transfusions, and dialysis. Antibiotics may also be prescribed to treat the underlying infection. In some cases, plasma exchange may be used to reduce the amount of toxins in the blood. In severe cases, a kidney transplant may be necessary.

1. Age: Children under the age of 5 are at highest risk.
2. Immunosuppression: People with weakened immune systems are more likely to develop HUS.
3. Exposure to Streptococcus pneumoniae: People who have been exposed to the bacteria are at higher risk.
4. Genetics: Certain genetic mutations can increase the risk of developing HUS.
5. Certain medications: Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can increase the risk of developing HUS.

At this time, there is no specific cure or medication for Streptococcus pneumoniae-associated hemolytic uremic syndrome (HUS). Treatment typically involves supportive care, such as dialysis, to help manage the symptoms and complications of the condition. Antibiotics may be used to treat the underlying infection, and medications may be used to help reduce inflammation and prevent further damage to the kidneys.