Retinal macular dystrophy type 2 (also known as Best disease) is a rare genetic disorder that affects the macula, the part of the eye responsible for central vision. It is characterized by the gradual deterioration of the macula, leading to decreased central vision and eventual blindness. Symptoms typically begin in childhood and worsen over time. Treatment options are limited and may include vitamin A supplementation, laser therapy, and surgery.

The symptoms of Retinal Macular Dystrophy Type 2 (also known as Best Disease) include:

-Decreased central vision

-Distorted vision

-Blurred vision

-Difficulty reading

-Difficulty recognizing faces

-Difficulty seeing colors

-Difficulty adapting to low light

-Difficulty driving at night

-Sensitivity to glare

-Central scotoma (blind spot in the center of the visual field)

-Decreased contrast sensitivity

-Decreased visual acuity

Retinal macular dystrophy type 2 (also known as Best disease) is an inherited disorder caused by mutations in the VMD2 gene. This gene provides instructions for making a protein called bestrophin, which is found in the cells of the retina. Mutations in the VMD2 gene lead to a decrease in the amount of bestrophin protein, which disrupts the normal functioning of the retina and can lead to vision loss.

1. Vitamin A supplementation: Vitamin A supplementation is often recommended for people with retinal macular dystrophy type 2. This can help slow the progression of the disease and improve vision.

2. Low vision aids: Low vision aids such as magnifiers and special glasses can help people with retinal macular dystrophy type 2 to make the most of their remaining vision.

3. Surgery: In some cases, surgery may be recommended to improve vision. This may involve laser treatment or the implantation of a miniature telescope.

4. Gene therapy: Gene therapy is a promising new treatment for retinal macular dystrophy type 2. This involves injecting a healthy gene into the eye to replace the faulty gene that causes the condition.

5. Clinical trials: Clinical trials are ongoing to investigate new treatments for retinal macular

1. Age: Risk increases with age.
2. Genetics: Retinal macular dystrophy type 2 is an inherited disorder.
3. Family history: Having a family history of the disorder increases the risk.
4. Smoking: Smoking increases the risk of developing the disorder.
5. Diabetes: People with diabetes are at an increased risk of developing the disorder.
6. High blood pressure: High blood pressure can increase the risk of developing the disorder.
7. High cholesterol: High cholesterol levels can increase the risk of developing the disorder.
8. Obesity: Being overweight or obese can increase the risk of developing the disorder.

At this time, there is no cure for retinal macular dystrophy type 2. However, there are medications that can help slow the progression of the disease and improve vision. These medications include anti-VEGF injections, photodynamic therapy, and laser photocoagulation. Additionally, low vision aids such as magnifiers and telescopic lenses can help improve vision.