Progressive bifocal chorioretinal atrophy (PBCRA) is a rare, inherited eye disorder that affects the retina and choroid, the layers of tissue that line the back of the eye. It is characterized by progressive degeneration of the retinal pigment epithelium (RPE) and choroid, resulting in vision loss. Symptoms of PBCRA include decreased vision, night blindness, and the presence of yellowish spots in the retina. Treatment for PBCRA is limited and typically involves the use of low vision aids and other supportive measures.

The symptoms of Progressive bifocal chorioretinal Atrophy (PBCRA) include:

-Decreased vision in the affected eye(s)
-Distorted vision
-Blurred vision
-Decreased night vision
-Sensitivity to light
-Floaters
-Flashes of light
-Reduced color vision
-Loss of peripheral vision
-Loss of central vision
-Retinal detachment
-Retinal holes or tears
-Retinal pigmentary changes

The exact cause of progressive bifocal chorioretinal atrophy is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Some possible causes include:

• Genetic mutations
• Exposure to ultraviolet light
• Exposure to certain toxins
• Autoimmune disorders
• Vitamin A deficiency
• Certain medications
• Radiation therapy
• Trauma to the eye

Unfortunately, there is no known cure for progressive bifocal chorioretinal atrophy. Treatment is focused on managing the symptoms and slowing the progression of the disease. This may include regular eye exams, laser treatments, and medications to reduce inflammation. In some cases, surgery may be recommended to improve vision. Additionally, lifestyle modifications such as avoiding bright lights and wearing sunglasses may help to reduce symptoms.

1. Age: Progressive bifocal chorioretinal atrophy is more common in older individuals.

2. Genetics: Progressive bifocal chorioretinal atrophy is an inherited condition, and individuals with a family history of the condition are at an increased risk.

3. Sun exposure: Prolonged exposure to ultraviolet (UV) light from the sun can increase the risk of developing progressive bifocal chorioretinal atrophy.

4. Smoking: Smoking has been linked to an increased risk of developing progressive bifocal chorioretinal atrophy.

5. Diabetes: Individuals with diabetes are at an increased risk of developing progressive bifocal chorioretinal atrophy.

Unfortunately, there is no known cure or medications for Progressive Bifocal Chorioretinal Atrophy. Treatment is focused on managing the symptoms and slowing the progression of the disease. This may include regular eye exams, lifestyle modifications, and the use of low vision aids.