Native American myopathy (NAM) is a rare, inherited neuromuscular disorder that primarily affects members of certain Native American tribes, including the Choctaw, Chickasaw, and Seminole. It is characterized by progressive muscle weakness and wasting, as well as joint contractures and scoliosis. NAM is caused by a mutation in the gene encoding the protein titin, which is involved in the structure and function of muscle fibers. Treatment is supportive and includes physical therapy, orthopedic braces, and medications to reduce muscle spasms.

The symptoms of Native American myopathy vary from person to person, but generally include muscle weakness, muscle pain, and difficulty walking. Other symptoms may include difficulty swallowing, drooping eyelids, and difficulty breathing. In some cases, people with Native American myopathy may also experience joint pain, fatigue, and difficulty speaking.

Native American myopathy is a rare, inherited disorder that affects the muscles and is caused by a genetic mutation. The exact cause of the mutation is unknown, but it is believed to be related to a gene that is passed down through families. Other possible causes include environmental factors, such as exposure to toxins or radiation, or a combination of genetic and environmental factors.

The treatments for Native American myopathy vary depending on the severity of the condition. Generally, treatment focuses on managing symptoms and preventing further muscle damage. This may include physical therapy, occupational therapy, and medications to reduce muscle spasms and pain. In some cases, surgery may be necessary to correct any underlying structural issues. Additionally, lifestyle modifications such as avoiding strenuous activities and maintaining a healthy diet may help to reduce symptoms.

1. Native American ancestry
2. Age (most commonly seen in adults over the age of 40)
3. Gender (more common in males)
4. Family history of Native American myopathy
5. Exposure to certain environmental toxins
6. Certain medications (such as statins)
7. Alcohol consumption
8. Smoking
9. Obesity
10. Diabetes

At this time, there is no known cure for Native American myopathy. However, medications can be used to help manage the symptoms of the condition. These medications may include muscle relaxants, anticonvulsants, and immunosuppressants. Physical therapy and lifestyle modifications may also be recommended to help manage the symptoms.