About Myasthenia Gravis and Pregnancy

What is Myasthenia Gravis and Pregnancy?

Myasthenia gravis is an autoimmune disorder that affects the muscles and causes muscle weakness and fatigue. It is caused by a breakdown in communication between the nerves and muscles. During pregnancy, the symptoms of myasthenia gravis can worsen due to the increased levels of hormones in the body. Women with myasthenia gravis should be monitored closely during pregnancy and delivery, as the disease can cause complications. Treatment for myasthenia gravis during pregnancy may include medications, such as anticholinesterase drugs, to help reduce muscle weakness and fatigue.

What are the symptoms of Myasthenia Gravis and Pregnancy?

Myasthenia Gravis:

The most common symptoms of myasthenia gravis include:

• Muscle weakness, especially in the face, neck, and arms
• Difficulty speaking, chewing, and swallowing
• Drooping eyelids
• Double vision
• Fatigue
• Difficulty breathing

Pregnancy:

The most common symptoms of pregnancy include:

• Missed period
Nausea and vomiting
• Breast tenderness and swelling
• Fatigue
• Frequent urination
• Mood swings
• Food cravings and aversions
• Lightheadedness
• Backaches

What are the causes of Myasthenia Gravis and Pregnancy?

Myasthenia Gravis:
Myasthenia gravis is an autoimmune disorder caused by the production of antibodies that attack the receptors for the neurotransmitter acetylcholine at the neuromuscular junction. This results in muscle weakness and fatigue. The exact cause of myasthenia gravis is unknown, but it is believed to be caused by a combination of genetic and environmental factors.

Pregnancy:
Pregnancy can cause myasthenia gravis due to the increased production of hormones, such as progesterone, which can interfere with the normal functioning of the neuromuscular junction. Additionally, the body's immune system is weakened during pregnancy, which can lead to an increased risk of developing autoimmune disorders such as myasthenia gravis.

What are the treatments for Myasthenia Gravis and Pregnancy?

Myasthenia Gravis:

1. Medications: Medications such as cholinesterase inhibitors, immunosuppressants, and corticosteroids are used to treat myasthenia gravis.

2. Surgery: Surgery may be recommended to remove the thymus gland, which is believed to be the source of the antibodies that cause myasthenia gravis.

3. Plasmapheresis: Plasmapheresis is a procedure in which the patient’s blood is filtered to remove the antibodies that are causing the myasthenia gravis.

4. Intravenous Immunoglobulin (IVIG): IVIG is a treatment that involves infusing the patient with antibodies from healthy donors to help reduce the symptoms of myasthenia gravis.

What are the risk factors for Myasthenia Gravis and Pregnancy?

Risk factors for Myasthenia Gravis and Pregnancy include:

1. Age: Women over the age of 40 are at higher risk for developing Myasthenia Gravis during pregnancy.

2. Previous history of Myasthenia Gravis: Women who have had Myasthenia Gravis prior to pregnancy are at higher risk for developing it during pregnancy.

3. Family history of Myasthenia Gravis: Women with a family history of Myasthenia Gravis are at higher risk for developing it during pregnancy.

4. Autoimmune disorders: Women with autoimmune disorders such as lupus, rheumatoid arthritis, or thyroid disease are at higher risk for developing Myasthenia Gravis during pregnancy.

5. Medications: Certain medications, such as beta-blockers,

Is there a cure/medications for Myasthenia Gravis and Pregnancy?

Myasthenia gravis is an autoimmune disorder that affects the muscles and can cause muscle weakness and fatigue. There is no cure for myasthenia gravis, but medications can help manage the symptoms. During pregnancy, the medications used to treat myasthenia gravis are generally considered safe. However, it is important to discuss any medications with your doctor before taking them during pregnancy.