About Medullary Thyroid Carcinoma

What is Medullary Thyroid Carcinoma?

Medullary thyroid carcinoma (MTC) is a rare type of thyroid cancer that develops in the C cells of the thyroid gland. It is usually caused by a genetic mutation and is more common in people with a family history of the disease. Symptoms of MTC can include a lump in the neck, difficulty swallowing, hoarseness, and coughing. Treatment typically involves surgery to remove the affected thyroid gland, followed by radiation and/or chemotherapy.

What are the symptoms of Medullary Thyroid Carcinoma?

Common symptoms of Medullary Thyroid Carcinoma (MTC) include:

-Neck swelling
-Hoarseness
-Difficulty swallowing
-Coughing
-Shortness of breath
-Pain in the neck, throat, or jaw
-Unexplained weight loss
-Fatigue
-Frequent fevers
-High levels of calcium in the blood (hypercalcemia)
-Nausea and vomiting
-Diarrhea
-Frequent urination
-Muscle weakness
-Paralysis of the nerves that control the eyes and face (cranial nerve palsy)
-Enlarged lymph nodes in the neck

What are the causes of Medullary Thyroid Carcinoma?

Medullary thyroid carcinoma (MTC) is a rare type of thyroid cancer that is caused by a genetic mutation in the RET gene. This mutation is usually inherited, but it can also occur spontaneously. Other risk factors for MTC include a family history of the disease, certain inherited syndromes, and exposure to radiation.

What are the treatments for Medullary Thyroid Carcinoma?

The treatment for Medullary Thyroid Carcinoma (MTC) depends on the stage of the cancer and the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, and/or hormone therapy. Surgery is the most common treatment for MTC and may involve removing the entire thyroid gland (total thyroidectomy) or just the affected part of the gland (partial thyroidectomy). Radiation therapy may be used to treat any remaining cancer cells after surgery. Chemotherapy and targeted therapy may be used to treat advanced or recurrent MTC. Hormone therapy may be used to reduce the production of hormones that can stimulate the growth of MTC cells.

What are the risk factors for Medullary Thyroid Carcinoma?

1. Familial Medullary Thyroid Carcinoma (FMTC): Having a family history of FMTC increases the risk of developing the disease.

2. Multiple Endocrine Neoplasia Type 2 (MEN2): This is an inherited disorder that increases the risk of developing Medullary Thyroid Carcinoma.

3. RET Proto-Oncogene Mutation: A mutation in the RET proto-oncogene increases the risk of developing Medullary Thyroid Carcinoma.

4. Radiation Exposure: Exposure to radiation, such as radiation therapy for other cancers, increases the risk of developing Medullary Thyroid Carcinoma.

5. Age: The risk of developing Medullary Thyroid Carcinoma increases with age.

Is there a cure/medications for Medullary Thyroid Carcinoma?

Yes, there are treatments available for Medullary Thyroid Carcinoma. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, and hormone therapy. Your doctor will discuss the best treatment plan for you based on the stage and type of cancer.