Ivemark Syndrome is a rare genetic disorder that affects the development of the heart, liver, and other organs. It is caused by a mutation in the SMAD4 gene, which is responsible for the production of a protein that helps regulate cell growth and development. Symptoms of Ivemark Syndrome include abnormal heart structure, liver dysfunction, and malformations of the intestines, kidneys, and other organs.

The symptoms of Ivemark Syndrome vary from person to person, but may include:

-Abnormal development of the liver, spleen, and intestines
-Underdeveloped or absent gallbladder
-Abnormal heart structure
-Abnormal kidney structure
-Abnormal development of the pancreas
-Abnormal development of the lungs
-Abnormal development of the skeleton
-Low birth weight
-Feeding difficulties
-Growth retardation
-Developmental delays
-Cleft lip and/or palate
-Hearing loss
-Vision problems
-Cognitive impairments
-Seizures
-Kidney and/or liver failure

Ivemark Syndrome is a rare genetic disorder caused by a mutation in the NSDHL gene. This gene is responsible for producing an enzyme that helps break down fatty acids in the body. When this gene is mutated, it can lead to a buildup of fatty acids in the body, which can cause the symptoms associated with Ivemark Syndrome.

The treatments for Ivemark Syndrome vary depending on the severity of the condition and the individual patient. Generally, treatment focuses on managing the symptoms and complications associated with the condition. This may include surgery to correct any malformations, medications to treat any associated conditions, and physical and occupational therapy to help with any developmental delays. In some cases, a feeding tube may be necessary to ensure adequate nutrition. Genetic counseling may also be recommended for families affected by Ivemark Syndrome.

The exact cause of Ivemark Syndrome is unknown, but it is believed to be caused by a genetic mutation. Risk factors for Ivemark Syndrome include a family history of the condition, being of a certain ethnic background (such as Ashkenazi Jewish or Finnish), and being born prematurely.

Unfortunately, there is no cure for Ivemark Syndrome. However, there are medications and treatments available to help manage the symptoms. These include medications to help with breathing, nutrition, and other medical issues. Additionally, physical and occupational therapy can help improve the quality of life for those with Ivemark Syndrome.