Inflammatory pseudotumor of the liver (IPTL) is a rare benign tumor-like lesion of the liver that is composed of inflammatory cells and fibrous tissue. It is usually asymptomatic and is often discovered incidentally during imaging studies. Treatment is usually not necessary, but in some cases, surgical resection may be recommended.

The most common symptom of inflammatory pseudotumor of the liver is abdominal pain. Other symptoms may include nausea, vomiting, fever, jaundice, and weight loss. In some cases, the tumor may cause blockage of the bile ducts, leading to further complications.

The exact cause of inflammatory pseudotumor of the liver is unknown. However, it is believed to be related to an abnormal immune response to an infection or injury. Other possible causes include autoimmune diseases, medications, and certain genetic conditions.

The treatment for inflammatory pseudotumor of the liver depends on the size and location of the tumor. In some cases, the tumor may be monitored with imaging tests and no treatment is necessary. In other cases, treatment may include:

1. Surgery: Surgery may be recommended to remove the tumor if it is causing symptoms or if it is large.

2. Radiation therapy: Radiation therapy may be used to shrink the tumor or to reduce symptoms.

3. Chemotherapy: Chemotherapy may be used to shrink the tumor or to reduce symptoms.

4. Immunotherapy: Immunotherapy may be used to reduce inflammation and shrink the tumor.

5. Targeted therapy: Targeted therapy may be used to target specific molecules in the tumor cells and reduce inflammation.

1. Chronic alcohol abuse
2. Chronic viral hepatitis
3. Autoimmune diseases
4. Exposure to certain medications
5. Exposure to certain chemicals
6. Obesity
7. Diabetes
8. Smoking
9. Family history of liver disease

There is no known cure for inflammatory pseudotumor of the liver. Treatment typically involves medications to reduce inflammation and pain, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. In some cases, surgery may be necessary to remove the tumor.