Infantile digital fibromatosis is a rare, benign disorder that affects the fingers and toes of infants. It is characterized by the growth of fibrous tissue in the soft tissue of the fingers and toes, resulting in thickening and enlargement of the digits. The condition is usually diagnosed in the first few months of life and can cause pain, deformity, and difficulty with movement. Treatment typically involves surgical removal of the affected tissue.

The most common symptom of infantile digital fibromatosis is the presence of firm, rubbery, non-painful Nodules on the fingers and toes. These Nodules may be present at birth or may develop in the first few months of life. Other symptoms may include:

-Flexion contractures of the fingers and toes

-Joint stiffness

-Painful nodules

-Swelling of the affected area

-Decreased range of motion in the affected area

-Abnormal growth of the affected area

-Deformity of the affected area

The exact cause of infantile digital fibromatosis is unknown. It is thought to be a genetic disorder, as it is often seen in families with a history of the condition. It is also possible that environmental factors, such as exposure to certain chemicals or radiation, may play a role in the development of the condition.

1. Observation: In some cases, no treatment is necessary and the condition may resolve on its own.

2. Surgery: Surgery may be recommended to remove the fibromas if they are causing pain or discomfort, or if they are interfering with movement.

3. Cryotherapy: This involves freezing the fibromas with liquid nitrogen.

4. Laser therapy: This involves using a laser to destroy the fibromas.

5. Radiotherapy: This involves using radiation to destroy the fibromas.

6. Medication: Certain medications, such as corticosteroids, may be used to reduce inflammation and pain.

1. Genetic predisposition: Infantile digital fibromatosis is caused by a mutation in the gene encoding the protein TGFBR1.

2. Age: Infantile digital fibromatosis is most commonly seen in infants and young children.

3. Gender: Infantile digital fibromatosis is more common in males than females.

4. Ethnicity: Infantile digital fibromatosis is more common in individuals of African descent.

At this time, there is no cure for infantile digital fibromatosis. Treatment typically involves surgical removal of the fibromas, which can be done in a single procedure or in multiple stages. Medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to reduce inflammation and pain associated with the condition.