Idiopathic non-lupus full-house nephropathy is a rare kidney disorder that is characterized by the presence of multiple kidney diseases, including glomerulonephritis, tubulointerstitial nephritis, and vasculitis. It is an autoimmune disorder, meaning that the body’s own immune system attacks its own tissues. It is not related to lupus, and the cause is unknown. Symptoms may include high blood pressure, proteinuria, hematuria, and kidney failure. Treatment typically involves immunosuppressive medications and/or steroids.

The symptoms of Idiopathic non-lupus full-house nephropathy can vary depending on the severity of the condition. Common symptoms include:

-High blood pressure
-Proteinuria (excess protein in the urine)
-Edema (swelling)
-Fatigue
-Nausea
-Vomiting
-Loss of appetite
-Weight loss
-Itching
-Muscle cramps
-Frequent urination
-Dark-colored urine
-Foamy urine
-Blood in the urine

The exact cause of idiopathic non-lupus full-house nephropathy is unknown. However, some potential causes may include:

• Genetic predisposition
• Exposure to certain environmental toxins
• Autoimmune disorders
• Viral infections
• Certain medications
• High blood pressure
• Diabetes
• Kidney stones
• Kidney trauma

1. Medications: ACE inhibitors, angiotensin receptor blockers, diuretics, and calcium channel blockers can be used to reduce blood pressure and reduce proteinuria.

2. Diet: A low-salt, low-protein diet may be recommended to reduce the amount of protein in the urine.

3. Dialysis: Dialysis may be necessary if kidney function is severely impaired.

4. Kidney transplant: A kidney transplant may be necessary if kidney function is severely impaired and dialysis is not an option.

5. Immunosuppressants: Immunosuppressants such as cyclophosphamide and mycophenolate mofetil may be used to reduce inflammation and slow the progression of the disease.

1. Hypertension
2. Diabetes
3. Obesity
4. Smoking
5. Family history of kidney disease
6. African American ethnicity
7. High cholesterol
8. High levels of protein in the urine
9. Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs)
10. Long-term use of certain antibiotics

There is no cure for idiopathic non-lupus full-house nephropathy. Treatment focuses on controlling symptoms and slowing the progression of the disease. Medications such as angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and diuretics may be prescribed to help control blood pressure and reduce fluid retention. Other medications, such as immunosuppressants, may be prescribed to reduce inflammation and slow the progression of the disease.