Huriez syndrome is a rare genetic disorder that affects the development of the hands and feet. It is caused by a mutation in the gene that codes for the protein filamin A. Symptoms of Huriez syndrome include webbing of the fingers and toes, shortening of the fingers and toes, and underdevelopment of the nails.

The symptoms of Huriez syndrome include:

-Delayed physical development
-Intellectual disability
-Seizures
-Feeding difficulties
-Growth retardation
-Hearing loss
-Vision problems
-Abnormal facial features
-Abnormalities of the hands and feet
-Abnormalities of the heart and other organs
-Abnormalities of the skeleton
-Abnormalities of the skin

Huriez syndrome is a rare genetic disorder caused by mutations in the COL6A1 gene. This gene is responsible for producing a protein called collagen type VI alpha-1, which is important for the formation of connective tissue. Mutations in this gene can lead to a variety of symptoms, including joint contractures, muscle weakness, and skin abnormalities.

The treatment for Huriez syndrome is focused on managing the symptoms and complications associated with the condition. Treatment may include physical therapy, occupational therapy, speech therapy, orthopedic surgery, and medications to reduce inflammation and pain. In some cases, surgery may be necessary to correct joint deformities or to release tight muscles. Additionally, splints and braces may be used to help support weakened joints.

The main risk factor for Huriez syndrome is having a family history of the condition. Other risk factors include having a genetic mutation in the GJB2 gene, being of Ashkenazi Jewish descent, and having a history of consanguinity (marriage between close relatives).

At this time, there is no known cure for Huriez syndrome. Treatment focuses on managing the symptoms, which may include physical therapy, occupational therapy, speech therapy, and medications to help with muscle spasms and pain.