Hallux varus-preaxial polysyndactyly syndrome is a rare genetic disorder characterized by the presence of extra toes on the feet (polysyndactyly) and a deformity of the big toe (hallux varus). It is caused by a mutation in the HOXD13 gene. Symptoms may include webbing of the toes, extra toes, and a curved big toe. Treatment may include surgery to correct the deformity and remove any extra toes.

The symptoms of Hallux varus-preaxial polysyndactyly syndrome include:

-Abnormally shaped big toe (hallux varus)
-Extra toes or fingers (polydactyly)
-Fused or webbed toes or fingers
-Abnormal toe or finger placement (preaxial polydactyly)
-Abnormal foot shape
-Abnormal joint movement
-Abnormal bone growth
-Abnormal skin folds
-Abnormal nail growth
-Abnormal muscle development
-Abnormal tendon development
-Abnormal ligament development
-Abnormal joint development
-Abnormal bone development
-Abnormal cartilage development
-Abnormal joint pain
-Abnormal joint stiffness
-Abnormal joint swelling
-Abnormal joint instability

Hallux varus-preaxial polysyndactyly syndrome is a rare genetic disorder caused by a mutation in the HOXD13 gene. This gene is responsible for the development of the feet and hands. The mutation can be inherited from a parent or can occur spontaneously. It is also associated with other genetic disorders such as VACTERL syndrome and Holt-Oram syndrome.

Treatment for Hallux varus-preaxial polysyndactyly syndrome typically involves surgical correction of the deformity. This may involve releasing the tight ligaments and tendons, realigning the bones, and possibly fusing the joint. In some cases, a tendon transfer may be necessary to improve the alignment of the toes. In addition, physical therapy may be recommended to help improve range of motion and strength in the affected area.

1. Genetic predisposition: Hallux varus-preaxial polysyndactyly syndrome is an inherited disorder caused by a mutation in the HOXD13 gene.

2. Family history: Individuals with a family history of the disorder are at an increased risk of developing the condition.

3. Gender: The disorder is more common in males than females.

4. Age: The disorder is more likely to occur in infants and young children.

At this time, there is no known cure for Hallux varus-preaxial polysyndactyly syndrome. Treatment is focused on managing the symptoms and complications associated with the condition. This may include physical therapy, orthopedic surgery, and medications to reduce pain and inflammation.