About Gestational Trophoblastic Disease

What is Gestational Trophoblastic Disease?

Gestational trophoblastic disease (GTD) is a group of rare tumors that develop from cells that would normally become placenta during pregnancy. It is a type of cancer that affects the cells that form the placenta during pregnancy. GTD can range from a benign condition to a malignant tumor. Symptoms may include abnormal vaginal bleeding, abdominal pain, and nausea. Treatment may include surgery, chemotherapy, and/or radiation.

What are the symptoms of Gestational Trophoblastic Disease?

Common symptoms of Gestational Trophoblastic Disease (GTD) include:

-Vaginal bleeding
-Abdominal Pain or swelling
-Nausea and vomiting
-Fever
-Weight loss
-Fatigue
-Shortness of breath
-Amenorrhea (absence of menstrual periods)
-Hydatidiform mole (abnormal growth of the placenta)
-High levels of human chorionic gonadotropin (hCG) in the blood or urine

What are the causes of Gestational Trophoblastic Disease?

Gestational trophoblastic disease (GTD) is a rare form of cancer that affects the cells that normally form the placenta during pregnancy. The exact cause of GTD is unknown, but it is believed to be related to abnormal cell growth in the placenta. Risk factors for GTD include a history of molar pregnancy, a family history of GTD, and certain genetic mutations.

What are the treatments for Gestational Trophoblastic Disease?

The treatment for Gestational Trophoblastic Disease (GTD) depends on the type and stage of the disease. Generally, treatment options include chemotherapy, surgery, and radiation therapy. In some cases, a combination of these treatments may be used. In some cases, a hysterectomy may be recommended. In addition, supportive care such as blood transfusions, pain management, and nutritional support may be necessary.

What are the risk factors for Gestational Trophoblastic Disease?

1. Previous history of Gestational Trophoblastic Disease
2. Previous history of molar pregnancy
3. Previous history of multiple pregnancies
4. Advanced maternal age
5. Low socioeconomic status
6. Low body mass index
7. Exposure to certain environmental toxins
8. Exposure to certain medications
9. Family history of Gestational Trophoblastic Disease

Is there a cure/medications for Gestational Trophoblastic Disease?

Yes, there are treatments available for Gestational Trophoblastic Disease. Depending on the type and stage of the disease, treatment may include chemotherapy, surgery, radiation therapy, or a combination of these treatments. Medications used to treat Gestational Trophoblastic Disease include methotrexate, actinomycin D, and etoposide.