About Fixed drug eruption

What is Fixed drug eruption?

Fixed drug eruption (FDE) is a type of drug reaction that is characterized by a localized area of skin that becomes red, swollen, and itchy after taking a certain medication. The reaction usually occurs in the same area of the body each time the drug is taken. FDE is most commonly caused by certain antibiotics, such as sulfonamides, but can also be caused by other medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Treatment for FDE typically involves avoiding the medication that caused the reaction and using topical corticosteroids to reduce inflammation.

What are the symptoms of Fixed drug eruption?

The symptoms of fixed drug eruption include:

-A single, round, red patch on the skin that may be raised and itchy
-Smaller red patches that may appear around the original patch
-Blisters that may form on the patch
-Darkening of the skin in the affected area
-Pain, burning, or Itching in the affected area
-Swelling in the affected area
-Crusting or scaling of the skin in the affected area

What are the causes of Fixed drug eruption?

The exact cause of fixed drug eruption is unknown, but it is believed to be an allergic reaction to certain medications. Common triggers include antibiotics, such as sulfonamides and tetracyclines, non-steroidal anti-inflammatory drugs (NSAIDs), and anticonvulsants. Other possible triggers include barbiturates, antifungal medications, and certain herbal supplements.

What are the treatments for Fixed drug eruption?

1. Avoidance of the causative drug: The most important treatment for fixed drug eruption is to identify and avoid the causative drug.

2. Topical corticosteroids: Topical corticosteroids are often used to reduce inflammation and itching.

3. Systemic corticosteroids: Systemic corticosteroids may be prescribed to reduce inflammation and itching.

4. Antihistamines: Antihistamines may be prescribed to reduce itching.

5. Phototherapy: Phototherapy, or light therapy, may be used to reduce inflammation and itching.

6. Oral antibiotics: Oral antibiotics may be prescribed to reduce inflammation and prevent secondary infection.

7. Immunomodulators: Immunomodulators, such as cyclosporine, may be prescribed to reduce inflammation and itching.

What are the risk factors for Fixed drug eruption?

1. Age: Fixed drug eruptions are more common in adults than in children.
2. Gender: Women are more likely to develop fixed drug eruptions than men.
3. Medications: Certain medications, such as antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and anticonvulsants, are more likely to cause fixed drug eruptions.
4. Allergies: People with allergies or a history of allergies are more likely to develop fixed drug eruptions.
5. Skin type: People with darker skin tones are more likely to develop fixed drug eruptions.
6. Genetics: People with a family history of fixed drug eruptions are more likely to develop them.

Is there a cure/medications for Fixed drug eruption?

Fixed drug eruption is a type of allergic reaction to certain medications. Treatment typically involves avoiding the medication that caused the reaction and taking antihistamines or corticosteroids to reduce the symptoms. In some cases, a doctor may prescribe a topical steroid cream to reduce inflammation.