About Fibrous Dysplasia

What is Fibrous Dysplasia?

Fibrous dysplasia is a rare bone disorder in which normal bone is replaced by fibrous tissue. This can cause the affected bone to become weak and prone to fractures. It can also cause deformities in the affected area. Fibrous dysplasia can affect any bone in the body, but is most commonly found in the skull, face, and long bones of the arms and legs.

What are the symptoms of Fibrous Dysplasia?

The most common symptoms of Fibrous Dysplasia include:

-Pain in the affected area
-Swelling or deformity of the affected bone
-Fractures or breaks in the affected bone
-Weakness or Numbness in the affected area
-Limping or difficulty walking
-Fatigue
-Headaches
-Vision problems
-Hearing loss
-Abnormal growth of the affected bone

What are the causes of Fibrous Dysplasia?

Fibrous dysplasia is a genetic disorder caused by a mutation in the GNAS gene. This gene is responsible for producing a protein called Gs alpha, which helps regulate the activity of hormones in the body. The mutation causes the body to produce too much of this protein, leading to abnormal growth of fibrous tissue in the bones.

What are the treatments for Fibrous Dysplasia?

The main treatment for Fibrous Dysplasia is surgery. Depending on the severity of the condition, surgery may involve removing the affected bone and replacing it with a bone graft or metal implant. In some cases, medications such as bisphosphonates may be prescribed to help reduce pain and slow the progression of the condition. In addition, physical therapy may be recommended to help maintain range of motion and strength in the affected area.

What are the risk factors for Fibrous Dysplasia?

Fibrous Dysplasia is a genetic disorder, so the primary risk factor is having a family history of the disorder. Other risk factors include being female, being of African descent, and having a mutation in the GNAS gene.

Is there a cure/medications for Fibrous Dysplasia?

There is no cure for fibrous dysplasia, but medications can be used to manage symptoms. These medications include corticosteroids, bisphosphonates, and calcitonin. Surgery may also be used to treat the condition, depending on the severity of the symptoms.