Fibrolamellar carcinoma is a rare type of liver cancer that typically affects young adults. It is characterized by the presence of fibrous tissue and lamellar (layered) structures in the tumor. Symptoms of fibrolamellar carcinoma can include abdominal pain, jaundice, and weight loss. Treatment typically involves surgery to remove the tumor, followed by chemotherapy and/or radiation therapy.

The most common symptom of Fibrolamellar Carcinoma is a painless lump or mass in the abdomen. Other symptoms may include abdominal pain, nausea, vomiting, weight loss, and jaundice.

The exact cause of Fibrolamellar Carcinoma is unknown. However, research suggests that it may be caused by a mutation in the DNA of a gene called TP53. This gene is responsible for controlling cell growth and death, and when it is mutated, it can lead to uncontrolled cell growth and the development of cancer.

The primary treatment for Fibrolamellar Carcinoma is surgical resection, which involves removing the tumor and some surrounding tissue. In some cases, chemotherapy and/or radiation therapy may be used to shrink the tumor before surgery or to treat any remaining cancer cells after surgery. In some cases, targeted therapies such as immunotherapy may be used to help the body’s immune system fight the cancer. Clinical trials may also be available for patients with Fibrolamellar Carcinoma.

1. Age: Fibrolamellar carcinoma is most commonly diagnosed in adolescents and young adults between the ages of 15 and 30.

2. Gender: Fibrolamellar carcinoma is more common in males than females.

3. Family history: A family history of fibrolamellar carcinoma may increase the risk of developing the disease.

4. Genetic mutations: Certain genetic mutations, such as those in the TP53 gene, may increase the risk of developing fibrolamellar carcinoma.

5. Exposure to certain chemicals: Exposure to certain chemicals, such as vinyl chloride, may increase the risk of developing fibrolamellar carcinoma.

At this time, there is no known cure for Fibrolamellar Carcinoma. However, treatments such as surgery, chemotherapy, radiation therapy, and targeted therapy may be used to help manage the disease. Additionally, clinical trials are ongoing to explore new treatments for Fibrolamellar Carcinoma.