About Familial visceral myopathy

What is Familial visceral myopathy?

Familial visceral myopathy is a rare genetic disorder that affects the muscles of the internal organs, such as the stomach, intestines, and bladder. It is caused by mutations in the gene that codes for the protein dysferlin, which is involved in muscle repair and maintenance. Symptoms of familial visceral myopathy include abdominal pain, nausea, vomiting, constipation, and difficulty urinating. Treatment typically involves medications to reduce symptoms and physical therapy to help strengthen the affected muscles.

What are the symptoms of Familial visceral myopathy?

The symptoms of Familial Visceral Myopathy (FVM) vary from person to person, but may include:

- Abdominal pain
- Abdominal distention
- Nausea
- Vomiting
- Diarrhea
- Weight loss
- Weakness
- Fatigue
- Difficulty swallowing
- Difficulty breathing
- Abnormal heart rhythms
- Abnormal blood pressure
- Abnormal liver function tests
- Abnormal kidney function tests
- Abnormal muscle enzyme levels
- Muscle cramps
- Muscle stiffness
- Joint pain
- Joint swelling
- Joint stiffness
- Skin rash
- Low blood sugar

What are the causes of Familial visceral myopathy?

The exact cause of familial visceral myopathy is unknown. However, it is believed to be caused by a genetic mutation that affects the muscles of the digestive system. This mutation is thought to be inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene is needed to cause the condition.

What are the treatments for Familial visceral myopathy?

Treatment for familial visceral myopathy is focused on managing the symptoms and preventing complications. Treatment may include medications to reduce muscle spasms, physical therapy to improve muscle strength and flexibility, and lifestyle changes to reduce stress and fatigue. In some cases, surgery may be necessary to correct any structural abnormalities in the digestive tract.

What are the risk factors for Familial visceral myopathy?

1. Genetic predisposition: Familial visceral myopathy is an inherited disorder, meaning it is passed down from parent to child through a mutated gene.

2. Age: The disorder is more common in adults over the age of 40.

3. Gender: Men are more likely to be affected than women.

4. Ethnicity: Familial visceral myopathy is more common in people of African descent.

5. Family history: People with a family history of the disorder are more likely to develop it.

Is there a cure/medications for Familial visceral myopathy?

At this time, there is no cure for familial visceral myopathy. However, medications can be used to help manage the symptoms. These medications include muscle relaxants, antispasmodics, and anticholinergics. Additionally, physical therapy and lifestyle modifications can help to reduce symptoms.