Familial multiple nevi flammei is a rare genetic disorder characterized by the presence of multiple, flat, red-brown birthmarks on the skin. These birthmarks, known as nevi flammei, are caused by an abnormal accumulation of blood vessels in the skin. They typically appear on the face, neck, chest, and back, and may be present at birth or develop in early childhood. People with this condition may also have other skin abnormalities, such as moles, freckles, or café-au-lait spots.

The most common symptom of Familial multiple nevi flammei is the presence of multiple, flat, light brown or tan moles on the skin. These moles are usually found on the trunk, arms, and legs, and may be present at birth or develop during childhood. Other symptoms may include:

• Abnormal skin pigmentation
• Abnormal hair growth
• Abnormal nail growth
• Abnormal freckling
• Abnormal skin texture
• Abnormal skin color
• Abnormal moles
• Abnormal mole size
• Abnormal mole shape
• Abnormal mole color

Familial multiple nevi flammei is a rare genetic disorder caused by a mutation in the MITF gene. This gene is responsible for the production of a protein that helps regulate the production of melanin, the pigment that gives skin its color. The mutation causes an overproduction of melanin, resulting in the formation of multiple dark spots on the skin.

The treatment for Familial multiple nevi flammei is typically surgical excision. This is done to remove the nevi and reduce the risk of skin cancer. Other treatments may include cryotherapy, laser therapy, and topical medications. In some cases, a combination of treatments may be used.

1. Having a family history of Familial multiple nevi flammei
2. Having fair skin
3. Having a history of sunburns
4. Having a history of excessive sun exposure
5. Having a history of atypical moles
6. Having a history of skin cancer

At this time, there is no known cure for Familial multiple nevi flammei. However, there are medications that can be used to help manage the symptoms. These include topical corticosteroids, topical retinoids, and oral retinoids. Additionally, laser therapy and cryotherapy may be used to reduce the size and number of nevi.