Familial multiple lipomatosis (FML) is a rare genetic disorder characterized by the growth of multiple benign fatty tumors (lipomas) on the body. These tumors can occur anywhere on the body, but are most commonly found on the neck, shoulders, back, and abdomen. They are usually painless and do not cause any other health problems. Treatment is usually not necessary, but if the lipomas are causing discomfort or interfering with daily activities, they can be surgically removed.

The most common symptom of familial multiple lipomatosis is the presence of multiple, soft, fatty lumps (lipomas) on the body. These lumps can occur anywhere on the body, but are most commonly found on the neck, shoulders, back, and abdomen. Other symptoms may include:

• Pain or discomfort in the affected area

• Skin discoloration around the lipomas

• Difficulty moving due to the size and location of the lipomas

• Difficulty wearing certain types of clothing due to the size and location of the lipomas

• Low self-esteem due to the appearance of the lipomas

The exact cause of familial multiple lipomatosis is unknown. However, it is believed to be an inherited disorder caused by a genetic mutation. It is thought to be passed down in an autosomal dominant pattern, meaning that only one parent needs to have the gene mutation for a child to inherit the condition.

The treatments for Familial multiple lipomatosis vary depending on the severity of the condition. In some cases, no treatment is necessary. However, if the lipomas are causing pain or discomfort, they can be surgically removed. In some cases, liposuction may be used to remove the lipomas. In addition, medications such as corticosteroids may be prescribed to reduce inflammation and pain. In some cases, radiation therapy may be used to shrink the lipomas.

1. Family history: Familial multiple lipomatosis is an inherited disorder, so having a family history of the condition increases the risk of developing it.

2. Age: The condition is more common in adults, especially those over the age of 40.

3. Gender: Men are more likely to develop familial multiple lipomatosis than women.

4. Obesity: Being overweight or obese increases the risk of developing the condition.

5. Certain medical conditions: People with diabetes, high cholesterol, or high blood pressure are more likely to develop familial multiple lipomatosis.

At this time, there is no cure for familial multiple lipomatosis. Treatment typically involves surgical removal of the lipomas. Medications are not typically used to treat this condition.