Familial medullary thyroid carcinoma (FMTC) is a rare type of thyroid cancer that is inherited in an autosomal dominant pattern. It is caused by a mutation in the RET gene, which is responsible for controlling cell growth and development. FMTC is usually diagnosed in people between the ages of 30 and 50, and is more common in women than in men. Symptoms of FMTC include a lump in the neck, difficulty swallowing, hoarseness, and coughing. Treatment typically involves surgery to remove the affected thyroid gland, followed by radioactive iodine therapy and/or chemotherapy.

The most common symptom of familial medullary thyroid carcinoma is a lump in the neck. Other symptoms may include:

-Hoarseness or other changes in voice

-Difficulty swallowing

-Pain in the neck or throat

-Swollen lymph nodes in the neck

-Coughing

-Shortness of breath

-Unexplained weight loss

-Fatigue

-Fever

-Anemia

Familial medullary thyroid carcinoma (FMTC) is caused by a genetic mutation in the RET gene. This mutation is inherited in an autosomal dominant pattern, meaning that a person only needs to inherit one copy of the mutated gene from one parent to be at risk for developing FMTC.

1. Surgery: Surgery is the primary treatment for familial medullary thyroid carcinoma (FMTC). The goal of surgery is to remove the entire thyroid gland and any affected lymph nodes.

2. Radioactive iodine therapy: Radioactive iodine therapy may be used after surgery to destroy any remaining cancer cells.

3. External beam radiation therapy: External beam radiation therapy may be used to treat any remaining cancer cells or to reduce the risk of recurrence.

4. Targeted therapy: Targeted therapy is a type of treatment that uses drugs to target specific molecules involved in the growth and spread of cancer cells.

5. Chemotherapy: Chemotherapy may be used to treat advanced or recurrent FMTC.

1. Having a family history of Familial medullary thyroid carcinoma (FMTC)
2. Having a mutation in the RET gene
3. Being a female
4. Being of Ashkenazi Jewish descent
5. Having a history of radiation exposure to the neck or chest
6. Having a history of multiple endocrine neoplasia type 2 (MEN2)
7. Having a history of thyroid nodules or goiter
8. Having a history of other endocrine tumors, such as pheochromocytoma or parathyroid adenoma

Yes, there are treatments available for Familial Medullary Thyroid Carcinoma (FMTC). Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, and hormone therapy. Your doctor will determine the best treatment plan for you based on your individual needs.