Familial isolated clinodactyly of fingers is a rare genetic disorder characterized by a bent or curved fifth finger (pinky finger) on one or both hands. It is usually an isolated finding, meaning that it is not associated with any other medical conditions. It is usually inherited in an autosomal dominant pattern, meaning that only one copy of the gene is necessary for the disorder to be expressed.

The main symptom of familial isolated clinodactyly of fingers is a bent or curved fifth finger (pinky finger) on one or both hands. Other symptoms may include:

-A gap between the fourth and fifth fingers
-The fifth finger may be shorter than the other fingers
-The fifth finger may be rotated outward
-The fifth finger may be stiff and difficult to move
-The fifth finger may be held in a bent position
-The fifth finger may be curved toward the fourth finger

Familial isolated clinodactyly of fingers is a genetic condition caused by a mutation in the GLI3 gene. This gene is responsible for the development of the hands and feet during embryonic development. The mutation causes the fifth finger to be bent towards the fourth finger, and can also cause the fourth finger to be bent towards the fifth finger.

1. Observation: In some cases, no treatment is necessary and the clinodactyly may resolve on its own.

2. Splinting: Splinting the affected finger can help to correct the deformity.

3. Surgery: Surgery may be necessary to correct the deformity if it does not resolve on its own or with splinting. Surgery may involve releasing the tight structures around the affected finger or transferring tendons to help straighten the finger.

1. Genetic predisposition: Familial isolated clinodactyly of fingers is an inherited condition, meaning it is passed down from parents to their children.

2. Environmental factors: Exposure to certain environmental factors, such as radiation, may increase the risk of developing this condition.

3. Age: The risk of developing familial isolated clinodactyly of fingers increases with age.

4. Gender: Females are more likely to be affected than males.

Yes, there are treatments available for familial isolated clinodactyly of fingers. These include physical therapy, splinting, and surgery. Physical therapy can help to improve range of motion and strength in the affected fingers. Splinting can help to correct the position of the fingers and prevent further deformity. Surgery may be necessary to correct the deformity and improve function.