About Familial hyperaldosteronism type II

What is Familial hyperaldosteronism type II?

Familial hyperaldosteronism type II (FH-II) is an inherited disorder caused by a mutation in the gene that codes for the enzyme aldosterone synthase. This mutation results in an overproduction of aldosterone, a hormone that helps regulate sodium and potassium levels in the body. Symptoms of FH-II include high blood pressure, low potassium levels, and excessive thirst and urination. Treatment typically involves medications to control blood pressure and potassium supplements.

What are the symptoms of Familial hyperaldosteronism type II?

The symptoms of Familial Hyperaldosteronism Type II (FH-II) include:

-High blood pressure
-Headaches
-Muscle weakness
-Fatigue
-Excessive thirst
-Frequent urination
-Salt cravings
-Low potassium levels
-Weight loss
-Abdominal pain
-Nausea and vomiting
-Loss of appetite
-Confusion
-Depression
-Irritability
-Heart palpitations
-Lightheadedness

What are the causes of Familial hyperaldosteronism type II?

Familial hyperaldosteronism type II is caused by a genetic mutation in the gene that codes for the mineralocorticoid receptor (MR). This mutation causes the MR to be overactive, leading to increased levels of aldosterone in the body.

What are the treatments for Familial hyperaldosteronism type II?

1. Spironolactone: This is a medication that blocks the action of aldosterone, which helps to reduce the amount of sodium and water in the body and increase the amount of potassium.

2. Amiloride: This is a medication that blocks the action of aldosterone and helps to reduce the amount of sodium and water in the body and increase the amount of potassium.

3. Potassium-sparing diuretics: These medications help to reduce the amount of sodium and water in the body and increase the amount of potassium.

4. Mineralocorticoid receptor antagonists: These medications block the action of aldosterone and help to reduce the amount of sodium and water in the body and increase the amount of potassium.

5. Surgery: In some cases, surgery may be recommended to remove the

What are the risk factors for Familial hyperaldosteronism type II?

1. Family history of Familial Hyperaldosteronism Type II (FH-II)
2. Genetic mutations in the HSD3B2 gene
3. High levels of aldosterone in the blood
4. Low levels of potassium in the blood
5. High blood pressure
6. Abnormal heart rhythms
7. Muscle weakness
8. Headaches
9. Fatigue
10. Nausea
11. Vomiting
12. Loss of appetite
13. Weight loss
14. Excessive thirst
15. Excessive urination

Is there a cure/medications for Familial hyperaldosteronism type II?

Yes, there are medications and treatments available for Familial Hyperaldosteronism Type II. These include spironolactone, amiloride, and eplerenone. Additionally, surgery may be recommended to remove the affected adrenal gland.