About Familial Eosinophilic Cellulitis

What is Familial Eosinophilic Cellulitis?

Familial eosinophilic cellulitis is a rare skin disorder that is inherited in an autosomal dominant pattern. It is characterized by recurrent episodes of red, swollen, and itchy skin on the arms, legs, and trunk. The skin lesions may be accompanied by fever, joint pain, and lymph node enlargement. Treatment typically involves the use of topical and/or systemic corticosteroids.

What are the symptoms of Familial Eosinophilic Cellulitis?

The symptoms of Familial Eosinophilic Cellulitis (FEC) include:

-Painful, red, raised patches of skin
-Itching
-Swelling
-Blistering
-Crusting
-Thickening of the skin
-Discoloration of the skin
-Scarring
-Loss of skin elasticity
-Hair loss in the affected area

What are the causes of Familial Eosinophilic Cellulitis?

The exact cause of familial eosinophilic cellulitis is unknown. However, it is believed to be an inherited disorder caused by a genetic mutation. It is also thought to be related to an abnormal immune response, which causes the body to produce too many eosinophils, a type of white blood cell.

What are the treatments for Familial Eosinophilic Cellulitis?

1. Topical corticosteroids: These are the most commonly used treatment for Familial Eosinophilic Cellulitis. They can help reduce inflammation and itching.

2. Oral corticosteroids: These are used in more severe cases of Familial Eosinophilic Cellulitis. They can help reduce inflammation and itching.

3. Antihistamines: These can help reduce itching and inflammation.

4. Phototherapy: This is a type of light therapy that can help reduce inflammation and itching.

5. Immunosuppressants: These medications can help reduce inflammation and itching.

6. Biologic agents: These medications can help reduce inflammation and itching.

What are the risk factors for Familial Eosinophilic Cellulitis?

1. Genetic predisposition: Familial eosinophilic cellulitis is an inherited disorder, so having a family history of the condition increases the risk of developing it.

2. Age: Familial eosinophilic cellulitis is more common in children and young adults.

3. Gender: Females are more likely to develop familial eosinophilic cellulitis than males.

4. Allergies: People with allergies or asthma are more likely to develop familial eosinophilic cellulitis.

5. Immune system disorders: People with weakened immune systems, such as those with HIV/AIDS, are more likely to develop familial eosinophilic cellulitis.

Is there a cure/medications for Familial Eosinophilic Cellulitis?

There is no known cure for Familial Eosinophilic Cellulitis. Treatment typically involves topical and/or oral corticosteroids to reduce inflammation and itching. Other medications such as antihistamines, antibiotics, and immunosuppressants may also be prescribed to help manage symptoms.