Familial atrial tachyarrhythmia-infra-Hisian cardiac conduction disease is a rare genetic disorder that affects the electrical signals that control the heart's rhythm. It is caused by a mutation in the gene that codes for the protein connexin 40, which is responsible for the electrical conduction between the atria and the ventricles of the heart. Symptoms of this disorder include episodes of rapid heart rate (tachyarrhythmia), palpitations, dizziness, and fainting. Treatment typically involves medications to control the heart rate and lifestyle modifications to reduce the risk of complications.

The most common symptom of Familial atrial tachyarrhythmia-infra-Hisian cardiac conduction disease is an abnormally fast heart rate (tachycardia). Other symptoms may include:

-Palpitations

-Lightheadedness
-Shortness of breath
-Chest pain
-Fatigue
-Dizziness
-Fainting
-Irregular heartbeats
-Swelling in the legs and feet
-Difficulty concentrating

Familial atrial tachyarrhythmia-infra-Hisian cardiac conduction disease is caused by a genetic mutation in the SCN5A gene. This gene is responsible for producing a protein called sodium channel alpha subunit 5, which is essential for normal electrical conduction in the heart. Mutations in this gene can lead to abnormal electrical conduction in the heart, resulting in arrhythmias.

1. Medication: Medications such as beta-blockers, calcium channel blockers, and antiarrhythmic drugs can be used to help control the heart rate and reduce the risk of arrhythmias.

2. Ablation: Radiofrequency ablation is a procedure that uses heat to destroy the abnormal electrical pathways in the heart that are causing the arrhythmia.

3. Pacemaker: A pacemaker can be implanted to help regulate the heart rate and reduce the risk of arrhythmias.

4. Surgery: Surgery may be recommended in some cases to repair or replace the damaged heart tissue.

5. Lifestyle changes: Making lifestyle changes such as reducing stress, eating a healthy diet, and exercising regularly can help reduce the risk of arrhythmias.

1. Family history of the condition
2. Age (more common in adults)
3. Gender (more common in males)
4. Hypertension
5. Diabetes
6. Smoking
7. High cholesterol
8. Obesity
9. Stress
10. Excessive alcohol consumption
11. Certain medications (such as beta-blockers and calcium channel blockers)
12. Structural heart defects (such as atrial septal defect)
13. Abnormalities in the heart's electrical system (such as long QT syndrome)
14. Abnormalities in the heart's structure (such as cardiomyopathy)
15. Abnormalities in the heart's valves (such as mitral valve prolapse)

At this time, there is no known cure for Familial atrial tachyarrhythmia-infra-Hisian cardiac conduction disease. However, medications such as beta blockers, calcium channel blockers, and antiarrhythmic drugs may be used to help control the symptoms of the condition. Additionally, lifestyle modifications such as avoiding caffeine and alcohol, exercising regularly, and managing stress can help to reduce the risk of arrhythmias.