Ectrodactyly-polydactyly syndrome is a rare genetic disorder characterized by the absence of one or more fingers or toes (ectrodactyly) and the presence of extra fingers or toes (polydactyly). It is caused by a mutation in the HOXD13 gene. Symptoms may include webbing of the fingers and toes, syndactyly (fusion of the fingers or toes), and malformation of the hands and feet. Treatment may include surgery to correct the malformations and physical therapy to improve mobility.

The most common symptoms of Ectrodactyly-polydactyly syndrome include:

-Absence of one or more fingers or toes
-Presence of extra fingers or toes
-Abnormal shape of the hands or feet
-Underdeveloped or absent thumbs
-Underdeveloped or absent big toes
-Underdeveloped or absent little toes
-Underdeveloped or absent middle toes
-Underdeveloped or absent nails
-Underdeveloped or absent joints
-Underdeveloped or absent muscles
-Underdeveloped or absent tendons
-Underdeveloped or absent ligaments
-Underdeveloped or absent bones
-Underdeveloped or absent skin
-Underdeveloped or absent sweat glands
-Underdeveloped or absent hair follicles
-Underdeveloped or absent sebaceous glands
-Underdeveloped or absent sensory nerves
-Underdeveloped or absent

Ectrodactyly-polydactyly syndrome is a rare genetic disorder caused by a mutation in the TP63 gene. This gene is responsible for the development of the limbs and digits. The mutation can be inherited from a parent or can occur spontaneously.

Treatment for Ectrodactyly-polydactyly syndrome is typically focused on managing the physical symptoms of the condition. This may include surgery to correct any limb deformities, physical therapy to improve mobility, and orthopedic devices such as braces or prosthetics to help with movement. In some cases, reconstructive surgery may be necessary to improve the appearance of the affected limbs. Additionally, genetic counseling may be recommended to help families understand the condition and its potential implications.

1. Family history of Ectrodactyly-polydactyly syndrome
2. Maternal exposure to certain medications or environmental toxins
3. Maternal diabetes
4. Maternal advanced age
5. Maternal obesity
6. Maternal smoking
7. Maternal alcohol consumption
8. Maternal malnutrition

There is no cure for ectrodactyly-polydactyly syndrome, but there are treatments available to help manage the symptoms. These treatments may include physical therapy, occupational therapy, orthopedic surgery, and prosthetic devices. Medications may also be prescribed to help manage pain and other symptoms associated with the condition.