Dysplasia epiphysealis hemimelica (DEH), also known as Trevor disease, is a rare, non-hereditary skeletal disorder that affects the growth of bones in the hands and feet. It is characterized by the formation of multiple, symmetrical, cartilage-capped bone growths (osteochondromas) on the epiphyses (ends) of the long bones. These growths can cause deformity and pain, and can interfere with the normal growth and development of the affected bones. Treatment typically involves surgical removal of the growths, and may also include physical therapy and medications to reduce pain and inflammation.

The symptoms of Dysplasia Epiphysealis Hemimelica (Trevor Disease) include:

-Pain in the affected joint
-Swelling of the affected joint
-Limited range of motion in the affected joint
-Deformity of the affected joint
-Enlargement of the affected joint
-Bowing of the affected limb
-Muscle Weakness in the affected limb
-Tenderness in the affected joint
-Stiffness in the affected joint
-Decreased flexibility in the affected joint

The exact cause of Dysplasia Epiphysealis Hemimelica (Trevor Disease) is unknown. It is thought to be caused by a combination of genetic and environmental factors. Some researchers believe that it may be caused by a mutation in the gene that controls the growth of cartilage. Other possible causes include trauma, infection, or a metabolic disorder.

1. Non-surgical treatments:

- Physical therapy: This can help to reduce pain and improve range of motion.

- Bracing: This can help to reduce pain and improve range of motion.

- Non-steroidal anti-inflammatory drugs (NSAIDs): These can help to reduce pain and inflammation.

2. Surgical treatments:

- Osteotomy: This is a surgical procedure that involves cutting and realigning the bones to reduce pain and improve range of motion.

- Arthrodesis: This is a surgical procedure that involves fusing the bones together to reduce pain and improve range of motion.

- Arthroplasty: This is a surgical procedure that involves replacing the affected joint with an artificial joint to reduce pain and improve range of motion.

1. Genetic predisposition: Dysplasia Epiphysealis Hemimelica (Trevor Disease) is an inherited disorder, and it is believed to be caused by a mutation in the gene that codes for the protein collagen type II.

2. Age: The condition is most commonly seen in children between the ages of 5 and 10.

3. Gender: Boys are more likely to be affected than girls.

4. Family history: A family history of the condition increases the risk of developing it.

5. Trauma: Trauma to the affected area can increase the risk of developing the condition.

At this time, there is no known cure for Dysplasia Epiphysealis Hemimelica (Trevor Disease). Treatment typically involves pain management and physical therapy to help manage symptoms. Medications such as non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids may be prescribed to reduce inflammation and pain. Surgery may be recommended in some cases to correct deformities or to reduce pain.