DPM3-CDG (Data Protection Manager 3-Cloud Data Governance) is a cloud-based data governance solution from Microsoft that helps organizations protect their data in the cloud. It provides a comprehensive set of tools and services to help organizations manage, protect, and govern their data in the cloud. It helps organizations to ensure compliance with data privacy regulations, protect data from unauthorized access, and manage data access and usage.

The symptoms of DPM3-CDG vary from person to person, but may include:

-Developmental delays
-Intellectual disability
-Seizures
-Feeding difficulties
-Growth delays
-Hearing loss
-Vision problems
-Muscle weakness
-Coordination problems
-Heart defects
-Kidney problems
-Gastrointestinal issues
-Skin rashes
-Behavioral issues

DPM3-CDG is caused by mutations in the DPM3 gene. These mutations lead to a deficiency in the enzyme dolichol-phosphate mannosyltransferase 3, which is involved in the synthesis of glycoproteins. This deficiency results in a wide range of symptoms, including skeletal abnormalities, facial dysmorphism, intellectual disability, and seizures.

The treatments for DPM3-CDG vary depending on the individual and the severity of the condition. Treatment may include physical therapy, occupational therapy, speech therapy, dietary modifications, and medications to help manage symptoms. In some cases, surgery may be necessary to correct certain physical abnormalities. Additionally, genetic counseling may be recommended to help families understand the condition and plan for the future.

The risk factors for DPM3-CDG include:

1. Family history of the disorder
2. Mutation in the DPM3 gene
3. Consanguinity (marriage between close relatives)
4. Advanced maternal age
5. Exposure to certain environmental toxins or medications during pregnancy.

At this time, there is no cure for DPM3-CDG. However, there are medications that can help manage the symptoms of the disorder. These medications include anticonvulsants, anti-inflammatory drugs, and vitamin supplements. Additionally, physical and occupational therapy can help improve motor skills and coordination.