DOCK2 deficiency is a rare genetic disorder caused by mutations in the DOCK2 gene. It is characterized by recurrent infections, immune deficiency, and an increased risk of developing autoimmune diseases. Symptoms can include recurrent infections, recurrent sinusitis, recurrent ear infections, recurrent pneumonia, and recurrent skin infections. Other symptoms may include eczema, asthma, and allergies.

The symptoms of DOCK2 deficiency vary from person to person, but may include recurrent infections, recurrent sinusitis, recurrent otitis media, recurrent pneumonia, recurrent skin infections, recurrent viral infections, recurrent fungal infections, recurrent diarrhea, recurrent abdominal pain, recurrent vomiting, recurrent fever, recurrent joint pain, recurrent rashes, recurrent eczema, recurrent asthma, recurrent wheezing, recurrent bronchitis, recurrent lymphadenopathy, recurrent thrombocytopenia, recurrent anemia, recurrent neutropenia, recurrent lymphopenia, recurrent splenomegaly, recurrent hepatomegaly, recurrent lymphocytosis, recurrent neutrophilia, recurrent eosinophilia, recurrent monocytosis, recurrent anasarca, recurrent edema, recurrent hypotonia, recurrent developmental delay, recurrent growth retardation, recurrent

DOCK2 deficiency is caused by mutations in the DOCK2 gene, which is responsible for producing the DOCK2 protein. Mutations in this gene can lead to a variety of symptoms, including immunodeficiency, recurrent infections, and increased susceptibility to certain types of cancer.

The primary treatment for DOCK2 deficiency is supportive care. This includes regular monitoring of the patient's health, including their growth and development, as well as any potential infections. Additionally, immunoglobulin replacement therapy may be used to help boost the patient's immune system. Other treatments may include physical and occupational therapy, as well as speech therapy to help with any communication difficulties. In some cases, medications may be prescribed to help manage symptoms.

1. Family history of DOCK2 deficiency
2. Premature birth
3. Low birth weight
4. Exposure to certain medications during pregnancy
5. Exposure to certain environmental toxins during pregnancy
6. Exposure to certain infections during pregnancy
7. Genetic mutations in the DOCK2 gene

At this time, there is no cure or specific medications for DOCK2 deficiency. Treatment focuses on managing the symptoms and complications of the condition. This may include physical therapy, occupational therapy, speech therapy, and other supportive therapies. In some cases, medications may be prescribed to help manage symptoms such as seizures or inflammation.