Dentinogenesis imperfecta-short stature-hearing loss-intellectual disability syndrome is a rare genetic disorder characterized by abnormal dentin formation, short stature, hearing loss, and intellectual disability. It is caused by a mutation in the DSPP gene, which is responsible for the production of dentin sialophosphoprotein, a protein found in the dentin of teeth. Symptoms of this disorder include yellowish-brown discoloration of the teeth, delayed eruption of teeth, and increased susceptibility to dental caries. Other features may include short stature, hearing loss, and intellectual disability. Treatment is supportive and may include dental care, hearing aids, and speech therapy.