The treatments for Dejerine-Sottas Syndrome vary depending on the individual and the severity of the condition. Generally, treatments focus on managing the symptoms and improving the quality of life. These may include physical therapy, occupational therapy, speech therapy, orthopedic surgery, and medications to reduce muscle spasms. Other treatments may include braces, splints, and assistive devices to help with mobility. In some cases, surgery may be recommended to correct spinal deformities.