Deafness-genital anomalies-metacarpal and metatarsal synostosis syndrome (DGMS) is a rare genetic disorder characterized by hearing loss, genital anomalies, and fusion of the bones in the hands and feet (metacarpal and metatarsal synostosis). Affected individuals may also have other skeletal abnormalities, including short stature, scoliosis, and joint contractures. The hearing loss is usually sensorineural and may be mild to profound. The genital anomalies may include undescended testes, hypospadias, and micropenis in males, and labial fusion and clitoral enlargement in females. Treatment is based on the individual's symptoms and may include hearing aids, surgery, and physical therapy.