The primary treatment for D,L-2-hydroxyglutaric aciduria is dietary management. This includes avoiding foods that are high in protein, such as red meat, dairy, and eggs, and eating a diet that is low in carbohydrates and high in healthy fats and proteins. Additionally, supplements such as carnitine, thiamine, and biotin may be recommended to help manage symptoms. In some cases, medications such as valproic acid may be prescribed to help reduce the levels of D,L-2-hydroxyglutaric acid in the body. Finally, regular monitoring of blood and urine levels of D,L-2-hydroxyglutaric acid is recommended to ensure that the condition is being managed properly.