Cystinuria type B is a rare inherited disorder that affects the kidneys. It is caused by a mutation in the SLC3A1 gene, which is responsible for transporting the amino acid cystine out of the kidneys. People with this disorder have an increased risk of developing kidney stones due to the accumulation of cystine in the urine. Treatment typically involves dietary changes and medications to reduce the amount of cystine in the urine.

The symptoms of Cystinuria type B can vary from person to person, but may include:

-Frequent and painful urination
-Cloudy or bloody urine
-Abdominal pain
-Nausea and vomiting
-Fever
-Frequent urinary tract infections
-Kidney stones
-Loss of appetite
-Fatigue

Cystinuria type B is caused by a mutation in the SLC3A1 gene, which is responsible for the production of a protein called rBAT (renal-specific b0,+ amino acid transporter). This protein is responsible for transporting cystine, lysine, arginine, and ornithine out of the kidney tubules and into the urine. Mutations in this gene can cause cystine to accumulate in the kidneys, leading to cystinuria type B.

The main treatment for cystinuria type B is a low-cystine diet. This diet involves limiting foods that are high in cystine, such as red meat, poultry, fish, eggs, dairy products, and nuts. Additionally, medications such as alpha-mercaptopropionylglycine (tiopronin) and penicillamine may be prescribed to help reduce the amount of cystine in the urine. In some cases, surgery may be necessary to remove stones that have formed in the urinary tract.

1. Family history of cystinuria type B
2. Being male
3. Having a mutation in the SLC3A1 gene
4. Having a mutation in the SLC7A9 gene
5. Having a mutation in the SLC3A2 gene
6. Having a mutation in the SLC7A9 gene
7. Having a mutation in the SLC7A9 gene
8. Having a mutation in the SLC7A9 gene
9. Having a mutation in the SLC7A9 gene
10. Having a mutation in the SLC7A9 gene
11. Having a mutation in the SLC7A9 gene
12. Having a mutation in the SLC7A9 gene
13. Having a mutation in the SLC7A9 gene
14. Having

Yes, there are medications available to treat cystinuria type B. These medications work by increasing the amount of cystine that is excreted in the urine, which helps to reduce the risk of kidney stones. Some of the medications used to treat cystinuria type B include thiola, tiopronin, and captopril. Additionally, dietary changes, such as increasing fluid intake and reducing the amount of animal proteins in the diet, can help to reduce the risk of kidney stones.