Cutaneous T-cell lymphomas (CTCLs) are a group of rare, non-Hodgkin lymphomas that affect the skin. They are caused by a type of white blood cell called a T-cell, which normally helps the body fight infection. In CTCLs, the T-cells become abnormal and start to grow out of control, forming tumors in the skin. Symptoms of CTCLs can include red, scaly patches on the skin, itching, and swollen lymph nodes. Treatment options for CTCLs include topical medications, radiation therapy, chemotherapy, and immunotherapy.