Cutaneous T-Cell Lymphoma (CTCL) is a type of non-Hodgkin lymphoma that affects the skin. It is a type of cancer that starts in the white blood cells called T-cells, which are part of the body’s immune system. CTCL usually appears as patches or plaques on the skin, but can also affect the lymph nodes, blood, and internal organs. Symptoms of CTCL can include red, scaly patches or plaques on the skin, itching, and swollen lymph nodes. Treatment for CTCL may include topical medications, radiation therapy, chemotherapy, and/or immunotherapy.