Craniofacial conodysplasia is a rare genetic disorder characterized by malformations of the skull and facial bones. It is caused by a mutation in the gene that codes for the protein connexin 26. Symptoms of this disorder include a small head, a flattened face, a short nose, and a cleft palate. Other features may include hearing loss, vision problems, and intellectual disability. Treatment typically involves surgery to correct the facial deformities and hearing aids to improve hearing.